Eight Class A-enrollment schools began their state tournament journey with quarterfinal play on Thursday, March 17, 2022 at the Maturi Pavilion on the University of Minnesota campus. Unseeded Minneota made its way to the semifinals with a quarterfinal upset win over top-seeded Mountain Iron-Buhl. The Vikings will take on another school with its nickname, Minneota. In the lower bracket semifinal, No. 2 Mayer Lutheran and No. 3 Hancock will meet after posting quarterfinal victories.